Located in the Kanto region, Cerulean City is directly in the junction of 4 routes: Route 4, Route 5, Route 9 and Route 24. Cerulean Cave, which is only open to players who have defeated Kanto's Elite Four, is also situated in this city.
Cerulean City is home to the Cerulean Gym, with Misty who specializes in Water-type Pokémon as the gym leader. Initially, a house which allows access to Route 5 and Route 9 is blocked by a police officer. He will only move away after Misty is defeated.
Fishing in this city is only possible by using the HM Surf.