Medicham is a humanoid, bipedal Pokémon that resembles a yoga practitioner. It has a gray body with red and yellow adornments. A red headpiece with three bulb-like extensions covers the upper portion of its head: one on top and one on either side. The bulb on top is short on a female Medicham. Its large, focused eyes are slightly covered by the headpiece, and its red lips seem to be in a rounded or puckered position. Its legs appear to be covered with puffy, red pants that have a large yellow spot on the knees and yellow bands next to the hips.
Through the power of meditation and fasting, Medicham has developed a sixth sense. This allows it to use psychokinetic powers, and it heightens its energy to enhance this sixth sense. It battles with elegant, dance-like movements, which it uses to dodge attacks and launch devastating blows. The anime has shown that it can sense aura. It only eats once per month. It lives in fields and mountains. It will hide by using its powers to blend into its surroundings.
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Through yoga training, it has honed its sixth sense. Its movements are elegant.